Cam Newton threw 52 passes in Carolina's loss to Philadelphia on Thursday. The last 15 QBs to throw 49+ passes in a regulation (non-OT) game all lost.
The last QB to throw 49+ passes in a regulation game and win was Tom Brady against the Jets last season, when he threw 50 passes and won 22-17.
Note that Carson Palmer threw 51 passes this season in a win against the 49ers, but that game ended in overtime. Brian Hoyer, the opposing QB, threw 49 passes, so both QBs met this criteria.
The last QB to throw 49+ passes in a regulation game and win was Tom Brady against the Jets last season, when he threw 50 passes and won 22-17.
Note that Carson Palmer threw 51 passes this season in a win against the 49ers, but that game ended in overtime. Brian Hoyer, the opposing QB, threw 49 passes, so both QBs met this criteria.