a slide from presentation at meeting from last week's CDC hearing on boosters.
ya see Moderna holding strong.....some question whether Moderna folks will need a booster....but Moderna claims their internal data shows it gonna absolutely be necessary....
ya see J&J (Janssen) the ones who need it now...but will be a month, at least, before they have enuf data to formally ask for boosters.
Some hi risk folks with J&J (over age 80, or with serious comorbidity) are asking their doctors to prescribe a booster now...Canada and Japan have already allowed not just that, but also mixing it up, making the booster shot an mRNA vaccine (Pfizer or Moderna)..
and you read this link how natural immunity, from having gotten covid, is generally not as good as vaccine immunity, sometimes way worse
https://www.nebraskamed.com/COVID/covid-19-studies-natural-immunity-versus-vaccination
nerdy discussion here on how vaccine effectiveness means and how it works:
https://threadreaderapp.com/thread/1430218372348878860.html
many virologists think this simple corona virus, with it's limited spike proteins being it's only game, has already reached peak fitness and don't expect any more serious variants or mutations to appear:
https://www.nature.com/articles/s41591-021-01421-7
but other viruses out there!.....they just found bats in Laos with corona viruses very very similar to covid:
https://www.nature.com/articles/d41586-021-02596-2
and one bat in particular was an impressive living petri dish: "one individual... was..infected by an alphacoronavirus and a betacoronavirus ...BLAST analysis of obtained sequences identied alphacoronavirus sequences of the Decacovirus, Pedacovirus, and Rhinacovirus subgenera and betacoronavirus sequences of the Nobecovirus and Sarbecovirus"
why some doctors are skeptical of boosters:
https://www.bmj.com/content/374/bmj.n2320
finally, a randomly controlled trial of mask effectiveness among thousands of folks in villages in Pakistan. Should have done this a year ago!
They found cloth masks don't work......surgical masks do have a modest benefit, but mostly to those over age 50...and after the researchers left these villages, the villagers all went back to wearning no masks...warning, pdf file:
https://www.poverty-action.org/sites/default/files/publications/Mask_RCT____Symptomatic_Seropositivity_083121.pdf
ya see Moderna holding strong.....some question whether Moderna folks will need a booster....but Moderna claims their internal data shows it gonna absolutely be necessary....
ya see J&J (Janssen) the ones who need it now...but will be a month, at least, before they have enuf data to formally ask for boosters.
Some hi risk folks with J&J (over age 80, or with serious comorbidity) are asking their doctors to prescribe a booster now...Canada and Japan have already allowed not just that, but also mixing it up, making the booster shot an mRNA vaccine (Pfizer or Moderna)..
and you read this link how natural immunity, from having gotten covid, is generally not as good as vaccine immunity, sometimes way worse
https://www.nebraskamed.com/COVID/covid-19-studies-natural-immunity-versus-vaccination
nerdy discussion here on how vaccine effectiveness means and how it works:
https://threadreaderapp.com/thread/1430218372348878860.html
many virologists think this simple corona virus, with it's limited spike proteins being it's only game, has already reached peak fitness and don't expect any more serious variants or mutations to appear:
https://www.nature.com/articles/s41591-021-01421-7
but other viruses out there!.....they just found bats in Laos with corona viruses very very similar to covid:
https://www.nature.com/articles/d41586-021-02596-2
and one bat in particular was an impressive living petri dish: "one individual... was..infected by an alphacoronavirus and a betacoronavirus ...BLAST analysis of obtained sequences identied alphacoronavirus sequences of the Decacovirus, Pedacovirus, and Rhinacovirus subgenera and betacoronavirus sequences of the Nobecovirus and Sarbecovirus"
why some doctors are skeptical of boosters:
https://www.bmj.com/content/374/bmj.n2320
finally, a randomly controlled trial of mask effectiveness among thousands of folks in villages in Pakistan. Should have done this a year ago!
They found cloth masks don't work......surgical masks do have a modest benefit, but mostly to those over age 50...and after the researchers left these villages, the villagers all went back to wearning no masks...warning, pdf file:
https://www.poverty-action.org/sites/default/files/publications/Mask_RCT____Symptomatic_Seropositivity_083121.pdf