Depending on where you bet, and obviously what lines you have now......
SD are moving into +5' so if you like them, I would think to take them nowish at the +6.
Washington are
trying to get to +3, but the books are adjusting prices rather than lines.....Might be telling us something
....but if you wait they MAY get to +3.
I don't see any other games moving to or from a key number (side or total).....although with the news Boston is out the Arizona total may well dip below 37.
Hope this helps, and sorry about the initial reply